PRODUCTS

Our affordable test kits are designed to operate even in resource-limited clinical laboratories, including medical camps. They require no special instruments or infrastructure, while providing clinically reliable test results for the detection of MDR-TB and XDR-TB in 60 min. The tests help the clinician or doctor to choose the appropriate antibiotic treatment from day one!

Rapid information about the drug-susceptibility pattern can assist clinicians to choose suitable treatment regimes and take appropriate infection control actions rather than prescribing empirical treatment, thereby helping to control the spread of drug resistance in the community.

We are continuously developing different diagnostic methods, including automated solutions to simplify the handling of bacterial samples even further. To begin with, we are happy to introduce our first product which we call mfloDx® MDR-TB!

 

The kits will initially be available for research use only, and each kit will contain:

  • 1 lateral flow cassette
  • 3 enzyme solutions
  • 1 amplification reaction mixture
  • 1 detection solution

 

mfloDx® MDR-TB

Simple. Multiplexable. Reliable.

The mfloDx® MDR-TB test can robustly distinguish single-nucleotide variants of the most common mutations [rpoB 531 (TCG/TTG) and katG 315 (AGC/ACC)] causing MDR-TB, and also verify the loss of the respective wild type. This combinatorial molecular diagnostic test produces visual signals on lateral flow cassettes (Swedish Patent pending) corresponding to the respective genotype-tags on lateral flow strips, in approximately 60 min. By detecting only these two clinically significant mutations, the test can detect about 86% of mono- or multi-resistant TB cases.

 

mfloDx® XDR-TB

Large Capacity. The Next Step.

Our mfloDx® XDR-TB test can be performed directly either on microscopy positive samples or after considering results from the mfloDx® MDR-TB test. The mfloDx ® XDR-TB test can detect the presence of MTC, katG 315 wt, katG 315 ACC, inhA -15 wt, inhA -15T,  rpoB 531 wt, rpoB 531 TTG, rpoB 526 wt, rpoB 526 TAC, gyrA 90 wt, gyrA 90 GTG, gyrA 94 wt, gyrA 94 GGC, rrs 1401 wt,and rrs 1401 G. The miniXDR-TB® test (Swedish Patent pending) can also produce clinically reliable information by developing visual signals on the respective genotype-tags on lateral flow strips, in approximately 60 min. This test can bring the XDR-TB genotypic detection time from 6 months to 60 min.

 

 

 
CONTACT INFORMATION

        Nobels Väg 3, Solna

 +46 727 600 752

                          info@empediagnostics.com

 

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